7: Infective Endocarditis : Pathology USMLE Step 1
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- Опубликовано: 13 апр 2025
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7: Infective Endocarditis : Pathology USMLE Step 1
Dive into the intricate pathology of infective endocarditis (IE) tailored for USMLE Step 1 preparation. IE is a microbial infection of the endocardial surface of the heart, often affecting the heart valves. The condition typically arises from bacteremia, with bacteria adhering to damaged endothelium and forming vegetations composed of platelets, fibrin, and bacteria. The etiology includes both bacterial and fungal pathogens, with the most common causative organisms being viridans streptococci, Staphylococcus aureus, and enterococci. Clinical manifestations vary widely, ranging from nonspecific symptoms such as fever, malaise, and weight loss to more specific signs such as Osler's nodes, Janeway lesions, Roth spots, and splinter hemorrhages. Diagnosis relies on Duke criteria, which encompass major criteria (positive blood cultures, evidence of endocardial involvement on echocardiography) and minor criteria (predisposing factors, fever, vascular phenomena, immunologic phenomena). Treatment involves prolonged antibiotic therapy tailored to the specific pathogen, often requiring intravenous antibiotics followed by oral agents, with surgical intervention indicated for complications such as valve destruction, heart failure, or persistent infection. Understanding the complex etiology, varied clinical presentations, diagnostic criteria, and management strategies of infective endocarditis is crucial for medical students preparing for board exams and future clinical practice. 📚
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The greastest doctor ❤
Thankyou so much sir it was really helpful 🎉
So nice of you
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Most welcome
Easiest explanation 💯💯
Appreciate that
How long is the treatment???
My favourite sir❤❤❤❤❤❤❤❤❤❤❤
What the name of the doctor who is explaning the lecture?
So so helpful. Thank you 🥳
Glad it was helpful!
Excellent 👌👌
Thank you! Cheers!
Wow nice explanation 😊
Thankyou sir for this very neat lecture
Thanks for liking
Sir. Which text book are you following? Please 🙏
Multiple resources like Robbins of course, Rubins, Pathoma and
First aid
Hatts off 👒
Dankie Dr💯
damn that was good
Nice video
So nice
Thank you so much sir
Most welcome
nice
Infections disease
Itna complicate krke kyu padha raha hai and jo cheeze padhate wqt bol raha hai unhe pura explain kr n adha adha bata raha hai